Jamestown massacre: Algonquians kill 347 English settlers around Jamestown, Virginia, a third of the colony's population, during the Second Anglo-Powhatan War.

The Indian massacre of 1622 took place in the English Colony of Virginia on March 22, 1621/22 (O.S./N.S.). The English explorer John Smith, though he was not an eyewitness, wrote in his History of Virginia that warriors of the Powhatan "came unarmed into our houses with deer, turkeys, fish, fruits,…