Paddle steamer Brother Jonathan docks in Fort Victoria (now Victoria, British Columbia), carrying smallpox-infected passengers from San Francisco. The ensuing epidemic killed an estimated two-thirds of First Nations in the province of British Columbia.

Brother Jonathan was a paddle steamer that struck an uncharted rock near Point St. George, off the coast of Crescent City, California, on July 30, 1865. The ship was carrying 244 passengers and crew, with a large shipment of gold. Only 19 people survived, making it the deadliest shipwreck up to…