The first Treaty of Hopewell is signed, by which the United States acknowledges Cherokee lands in what is now East Tennessee.

Three agreements, each known as a Treaty of Hopewell, were signed between representatives of the Congress of the United States and the Cherokee, Choctaw, and Chickasaw peoples. They were negotiated and signed at the Hopewell plantation in South Carolina over 45 days during the winter of 1785–86.